BPC-157
A chain of fifteen amino acids from gastric juice, and one of the most studied repair peptides there is.
| Property | Value |
|---|---|
| Type | Pentadecapeptide, 15 amino acids |
| Origin | Derived from a protein in human gastric juice |
| Research field | Gut lining, tendons, ligaments, connective tissue |
| Research status | Almost entirely preclinical |
| Form | Freeze dried powder, also as a capsule |
What it is
BPC stands for body protection compound. It is a fragment of a larger protein found in human gastric juice. That origin makes sense: the stomach wall has to repair itself continuously in an environment aggressive enough to dissolve food.
How it works
The mechanism recurring most often in the literature is angiogenesis: the formation of new small blood vessels. Without blood supply tissue does not heal, so a substance influencing that sits at the start of the repair process. Effects on growth factors in connective tissue and on nitric oxide production are also described.
What the research shows
There are hundreds of publications, centred on the gastrointestinal tract and on tendons and ligaments. Nearly all of it comes from cell culture and animal work. That matters: many publications is not the same as much evidence in humans.
Research status
Preclinical. Most of the work comes from animal models; well designed human studies are scarce.
Practical
Normally dissolves in bacteriostatic water. As a powder it keeps months to years in a freezer, in solution considerably less. Ask for the batch certificate of analysis with HPLC and MS; see reading a certificate of analysis.
This site is made by the team behind Apex Bio Research, a Dutch supplier of research peptides with a certificate of analysis per batch.
Visit the shopThis site explains what the scientific literature says about peptides. It is not medical advice and not a set of instructions. The substances discussed here are research compounds: they are not approved for use in humans or animals. If you have a health question, see a doctor.
Read next
Dissolving peptides: which solvent for what?
Bacteriostatic water, sterile water or dilute acetic acid. What the difference is, why some peptides refuse to dissolve and what to do then.
Repair peptides: BPC-157 and TB-500
Two peptides often named in one breath but working along very different routes. Where they come from and what the literature says.
TB-500 (Thymosin beta-4)
TB-500 in brief: the active fragment of thymosin beta-4, and what is known about cell movement and repair.