Tesamorelin
A GHRH analogue with a fatty acid group shielding the chain, known from research on abdominal fat.
| Property | Value |
|---|---|
| Type | GHRH analogue with a fatty acid group |
| Receptor | GHRH receptor |
| Research field | Growth hormone, fat around the organs |
| Research status | Approved in the US for a specific use |
| Form | Powder in a vial, cartridge, disposable pen |
What it is
A version of GHRH with a fatty acid group at the start of the chain. That group shields it from breakdown, so it lasts longer than sermorelin.
How it works
It prompts the pituitary to release growth hormone, within the body’s own regulation. In the literature the emphasis is on fat around the organs rather than subcutaneous fat.
What the research shows
This is one of the few substances in this field for which large controlled human studies were run, resulting in approval in the United States for a defined medical use. That puts the level of evidence here on a different footing from most peptides.
Research status
An approved medicine in the US for a specific indication. The product sold as a research compound is not that; it is a different product with a different status.
Practical
Long chain with a fatty acid tail: more sensitive to temperature swings than a short peptide. In solution its quality declines faster than as a powder.
This site is made by the team behind Apex Bio Research, a Dutch supplier of research peptides with a certificate of analysis per batch.
Visit the shopThis site explains what the scientific literature says about peptides. It is not medical advice and not a set of instructions. The substances discussed here are research compounds: they are not approved for use in humans or animals. If you have a health question, see a doctor.
Read next
The growth hormone axis: GHRH, ghrelin, GH and IGF-1
Four links, two buttons and a whole family of peptides. Why so many different substances exist that all drive the same hormone.
AOD-9604
AOD-9604 in brief: the fat breakdown part of growth hormone, cut loose from the rest of the chain.
CJC-1295 with DAC
CJC-1295 with DAC in brief: the same chain, with an addition that makes it last days instead of minutes.